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A short-tempered medical college student Arjun Reddy falls in love with his junior Preeti who shares an intimate relationship with him for years. The couple are forced to break up when Preeti's father arranges for her to be married to another man in her caste. The impact of the break-up affects Arjun who becomes an alcoholic and drug addict who realizes his ways and tries to redeem himself and get back to normal.